Electrolyte Disorders

Mineral and bone disorder related to kidney disease happens when there is an imbalance in your blood levels of calcium and phosphorus. This mineral imbalance can affect your bones, heart and blood vessels.

Calcium Imbalances

  • Kidney’s Role: Healthy kidneys regulate calcium levels by activating vitamin D, which helps the body absorb calcium from food, and by filtering excess calcium from the blood. 
  • CKD and Calcium: When kidneys are damaged by chronic kidney disease (CKD), they may not be able to perform these functions properly, leading to imbalances in calcium levels. 
  • Hypocalcemia (Low Calcium):
    • Kidney disease can cause low calcium levels, which can lead to bone weakness and an increased risk of fractures. 
    • Low calcium can also be linked to low vitamin D levels, which are common in CKD. 
    • Symptoms of low calcium include muscle cramps, tingling fingers, and abdominal cramps. 
  • Hypercalcemia (High Calcium):
    • While less common than low calcium, high calcium levels can also occur in kidney disease. 
    • Symptoms of high calcium include fatigue, weakness, loss of appetite, nausea, and vomiting. 
  • Calcium and Bone Health: Imbalances in calcium and phosphorus (another mineral regulated by the kidneys) can lead to mineral and bone disorders, causing bone weakness and increased risk of fractures. 
  • Calcium and Cardiovascular Health: Both low and high calcium levels can have implications for cardiovascular health, potentially leading to heart disease and stroke. 

Potassium Imbalances

  • Kidney’s Role: Healthy kidneys play a crucial role in regulating potassium levels by filtering excess potassium from the blood and excreting it in urine. 
  • CKD and Potassium: When kidneys are damaged, they may not be able to efficiently remove potassium, leading to high potassium levels (hyperkalemia). 
  • Hyperkalemia (High Potassium):
    • High potassium levels can be dangerous, especially for the heart. 
    • Symptoms of hyperkalemia include nausea, weakness, numbness, and a slow pulse. 
    • Hyperkalemia is a common complication of CKD, particularly in advanced stages. 
  • Hypokalemia (Low Potassium):
    • While less common, low potassium levels (hypokalemia) can also occur in kidney disease, especially in the early stages. 
    • Low potassium can cause muscle weakness, fatigue, and irregular heartbeats. 
  • Managing Potassium: People with CKD may need to follow a low-potassium diet to help manage potassium levels. 
  • Potassium and Diet: Working with a registered dietitian can help individuals with CKD learn about foods that are high in potassium and how to limit their intake. 
Electrolytes Test Vector Illustration. Isolated Body Fluid Label

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